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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 2
2005 3
2006 8
2007 3
2008 5
2009 3
2010 2
2011 2
2012 3
2013 3
2014 5
2015 4
2016 2
2017 3
2018 2
2019 2
2020 5
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2023 1
2024 0

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57 results

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Page 1
Decoding cell death signals in liver inflammation.
Brenner C, Galluzzi L, Kepp O, Kroemer G. Brenner C, et al. J Hepatol. 2013 Sep;59(3):583-94. doi: 10.1016/j.jhep.2013.03.033. Epub 2013 Apr 6. J Hepatol. 2013. PMID: 23567086 Free article. Review.
Inflammation can be either beneficial or detrimental to the liver, depending on multiple factors. Mild (i.e., limited in intensity and destined to resolve) inflammatory responses have indeed been shown to exert consistent hepatoprotective effects, contributing to tissue re …
Inflammation can be either beneficial or detrimental to the liver, depending on multiple factors. Mild (i.e., limited in intensity an …
Cathepsin H Knockdown Reverses Radioresistance of Hepatocellular Carcinoma via Metabolic Switch Followed by Apoptosis.
Chen Q, Qu S, Liang Z, Liu Y, Chen H, Ma S, Liu X. Chen Q, et al. Int J Mol Sci. 2023 Mar 9;24(6):5257. doi: 10.3390/ijms24065257. Int J Mol Sci. 2023. PMID: 36982347 Free PMC article.
Through these methods, we originally found CTSH knockdown (KD) perturbed aerobic glycolysis and enhanced aerobic respiration, and thus promoted apoptosis through up-regulation and the release of proapoptotic factors such as AIFM1, HTRA2, and DIABLO, consequently reducing r …
Through these methods, we originally found CTSH knockdown (KD) perturbed aerobic glycolysis and enhanced aerobic respiration, and thus promo …
Moringa oleifera Aqueous Leaf Extract Induces Cell-Cycle Arrest and Apoptosis in Human Liver Hepatocellular Carcinoma Cells.
Tiloke C, Phulukdaree A, Gengan RM, Chuturgoon AA. Tiloke C, et al. Nutr Cancer. 2019;71(7):1165-1174. doi: 10.1080/01635581.2019.1597136. Epub 2019 Apr 4. Nutr Cancer. 2019. PMID: 30945951
We investigated the apoptosis inducing effects of MO crude aqueous leaf extract (MOE) in human liver hepatocellular carcinoma (HepG(2)) cells. Methods: HepG(2), PBMCs and Hek293 cell viability was evaluated using MTT assay. ...Cell cycle, gammaH2AX, and cleaved PARP-1 were …
We investigated the apoptosis inducing effects of MO crude aqueous leaf extract (MOE) in human liver hepatocellular carcinoma (HepG(2 …
Adenosine induces apoptosis in human liver cancer cells through ROS production and mitochondrial dysfunction.
Ma Y, Zhang J, Zhang Q, Chen P, Song J, Yu S, Liu H, Liu F, Song C, Yang D, Liu J. Ma Y, et al. Biochem Biophys Res Commun. 2014 May 23;448(1):8-14. doi: 10.1016/j.bbrc.2014.04.007. Epub 2014 Apr 13. Biochem Biophys Res Commun. 2014. PMID: 24727456
Here we found that extracellular adenosine suppresses the cell growth by induction of apoptosis in BEL-7404 liver cancer cells, and identified a novel mechanism that extracellular adenosine triggers apoptosis by increasing Reactive Oxygen Species (ROS) production and mitoc …
Here we found that extracellular adenosine suppresses the cell growth by induction of apoptosis in BEL-7404 liver cancer cells, and i …
Inhibitor of apoptosis proteins (IAPs) as regulatory factors of hepatic apoptosis.
Wang K, Lin B. Wang K, et al. Cell Signal. 2013 Oct;25(10):1970-80. doi: 10.1016/j.cellsig.2013.06.003. Epub 2013 Jun 11. Cell Signal. 2013. PMID: 23770286 Review.
IAPs impede apoptotic process via membrane receptor-dependent (extrinsic) cascade and mitochondrial dependent (intrinsic) pathway. IAP-mediated apoptosis affects the progression of liver diseases. Therapeutic options of liver diseases may depend on the …
IAPs impede apoptotic process via membrane receptor-dependent (extrinsic) cascade and mitochondrial dependent (intrinsic) pathway. IAP-media …
SMAC mimetic birinapant inhibits hepatocellular carcinoma growth by activating the cIAP1/TRAF3 signaling pathway.
Ding J, Qin D, Zhang Y, Li Q, Li Y, Li J. Ding J, et al. Mol Med Rep. 2020 Mar;21(3):1251-1257. doi: 10.3892/mmr.2020.10908. Epub 2020 Jan 3. Mol Med Rep. 2020. PMID: 31922244 Free PMC article.
Annexin V-FITC and Transwell assays were used to assess the effect of birinapant pretreatment on the apoptotic rate and invasive ability of liver cancer cells. Lentivirus-mediated silencing of TRAF3 was performed in liver cancer cells. ...The present results suggest …
Annexin V-FITC and Transwell assays were used to assess the effect of birinapant pretreatment on the apoptotic rate and invasive ability of …
Tip30-induced apoptosis requires translocation of Bax and involves mitochondrial release of cytochrome c and Smac/DIABLO in hepatocellular carcinoma cells.
Shi M, Yan SG, Xie ST, Wang HN. Shi M, et al. Biochim Biophys Acta. 2008 Feb;1783(2):263-74. doi: 10.1016/j.bbamcr.2007.10.006. Epub 2007 Oct 24. Biochim Biophys Acta. 2008. PMID: 17997990 Free article.
Release of Smac/DIABLO from the mitochondria through the TIP30-P53-Bax cascade was required to remove the inhibitory effect of XIAP (X-linked Inhibitor of Apoptosis) and allowed apoptosis to proceed. Our results showed for the first time that Bax-dependent release of Smac/ …
Release of Smac/DIABLO from the mitochondria through the TIP30-P53-Bax cascade was required to remove the inhibitory effect of XIAP ( …
Alcoholic hepatitis versus non-alcoholic steatohepatitis: Levels of expression of some proteins involved in tumorigenesis.
Nguyen L, Masouminia M, Mendoza A, Samadzadeh S, Tillman B, Morgan T, French B, French S. Nguyen L, et al. Exp Mol Pathol. 2018 Feb;104(1):45-49. doi: 10.1016/j.yexmp.2017.12.007. Epub 2018 Jan 4. Exp Mol Pathol. 2018. PMID: 29307797 Free PMC article.
The 20 proteins tested are parts of the Ingenuity Canonical Pathway of Molecular Mechanisms of Cancer and include: RAP2B, NAIP, FYN, PAK6, SUV39H1, GNAI1, BAX, E2F3, CKDN2B, BAK1, BCL2, DIABLO, RASGRF2, GNA15, PIK3CB, BRCA1, MAP2K1, BIRC3, CDK2, and ATM. ...These results s …
The 20 proteins tested are parts of the Ingenuity Canonical Pathway of Molecular Mechanisms of Cancer and include: RAP2B, NAIP, FYN, PAK6, S …
Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats.
Xu XF, Zhang J. Xu XF, et al. Physiol Res. 2013;62(4):395-403. doi: 10.33549/physiolres.932515. Physiol Res. 2013. PMID: 23961899 Free article.
Treatment with saturated hydrogen saline prolonged the median survival time and reduced liver dysfunction. Moreover, saturated hydrogen saline significantly reduced pathological alterations in liver tissues, the number of ballooned hepatocytes, serum tumor necrosis …
Treatment with saturated hydrogen saline prolonged the median survival time and reduced liver dysfunction. Moreover, saturated hydrog …
Expression and activation of apoptosis-related molecules involved in interferon-alpha-mediated apoptosis in human liver cancer cells.
Yano H, Ogasawara S, Momosaki S, Akiba J, Nishida N, Kojiro S, Ishizaki H, Kojiro M. Yano H, et al. Int J Oncol. 2005 Jun;26(6):1645-52. Int J Oncol. 2005. PMID: 15870881
Interferon (IFN)-alpha directly inhibits proliferation of liver cancer cells by inducing apoptosis, but the molecular mechanisms by which IFN-alpha induces apoptosis in these cells are not fully understood. ...In conclusion, our results suggest IFN-alpha-mediated apoptosis …
Interferon (IFN)-alpha directly inhibits proliferation of liver cancer cells by inducing apoptosis, but the molecular mechanisms by w …
57 results